mRNA platform
State-of-the-art mRNA platforms to fit your needs
Our mRNA platforms and vast in-house experience help partners quickly optimize, screen and select an mRNA code, develop a candidate, and ensure effective & prime manufacturing of the mRNA from research grade to GMP scale. Our platform’s scale and flexibility is uniquely suited to respond to the needs of development partners across a wide range of therapeutic applications.
Platform features
Sequence Optimization
- Sequence optimization algorithms to increase the translation efficiency of the gene of interest by changing compatible codons
- 5’ and 3’ UTRs optimized for expression in human dendritic cells and myocytes
- C- terminal endosomal sorting signal demonstrated to enhance antigen presentation to CD4 and CD8 T cells
- High throughput screening of our in-house library of UTRs to find the best combination for maximized expression in your cell type of interest
Highly pure RNA
- Proprietary mRNA production processes (IVT and purification) optimized for increased purity and, as such, decrease impurity related immunogenicity and toxicity, allowing increased translation efficiency
Why work with us
Struggling with lack of internal expertise for your RNA therapeutics project or have multiple development needs? Our 30 years of experience and comprehensive platform offering can help.
Pioneering expertise
Integrated offering
Flexible partnership
Europe GMP facilities
Contact us
Contact us with any queries or for pricing information.