eTheRNA is developing an mRNA-based vaccine against metastatic melanoma consisting of naked mRNA encoding for TriMix and 5 tumor-associated antigens that is being administered intranodally (injected into the patient’s lymph nodes).
eTheRNA is developing an mRNA-based vaccine against HPV+ Head and neck cancer consisting of mRNA encoding for TriMix and E6/E7 antigens packaged in lipid nanoparticles administered intravenously.
Currently, a candidate is being tested in preclinical studies.
eTheRNA, in collaboration with Frame Therapeutics, is developing a mRNA-based vaccine against kidney cancer consisting of mRNA encoding for TriMix and frame shift neo-antigens packaged in lipid nanoparticles that will be administered intravenously.
Antigens in both the intranodal and intravenous products are interchangeable. By replacing the antigens, a range of oncology indications could be targeted. The technology is available for partnering and collaboration (see partnership page).
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